Multiple Myeloma Dictionary

leukopenia: A condition in which there are fewer cells for fighting infection and an overabundance of plasma cells.

lymphocytes: A group of white blood cells (of which there are five) that produce infection-fighting substances and include the B lymphocytes (B cells) and T lymphocytes (T cells).

M proteins: Known as "monoclonal proteins," these are generally indicators of plasma cell tumors when found in large amounts.

macroglobulinemia: A condition in which the spleen, lymph nodes and marrow exhibit abnormal plasma cell growth as evidenced by thickened blood.

monoclonal gammopathy of undetermined significance(MGUS): An excessive presence of immunoglobins and certain antibodies, which originate from abnormal plasma cells and leading to a strong potential for developing lymphoma and multiple myeloma.

myeloma: A cancer of the blood in which plasma cells develop abnormalities and begin to divide into clones that continue to produce the M protein antibody and may build up in marrow and solid bone, interfering with normal cell growth.

multiple myeloma: Also known as plasma cell myeloma, myelomatosis and Kahler's disease, this term indicates the presence of myeloma tumors at multiple sites, especially the bones, within the body.

osteoblasts: Cells residing in marrow that produce new bone and are also instrumental in controlling calcium structure in the bone itself.