Normal white blood cells are produced in the bone marrow, the soft spongy tissue that fills most of our bones. Some white blood cells develop into plasma cells, which help the immune system to fight infection by developing antibodies. They develop specific antibodies to fight specific diseases or infections.
Sometimes, the body's production of plasma cells gets out of control, well beyond the body's need to fight... Read more >
Multiple myeloma (MM) is diagnosed through a series of blood tests, x-rays, urinalysis and examination of bone marrow cells. MM produces distinct results on these tests, making diagnosis relatively straightforward once suspected.
Gel Electrophoresis: Blood Tests for IgA and IgG Antibodies
Blood tests that measure the level of white blood cells can return normal results even when multiple myeloma is present. A... Read more >
Bone Fractures, Anemia, Infections and Kidney Failure
A heightened risk of infection, bone fractures, kidney failure and blood disorders, such as anemia, are all common complications of multiple myeloma. Careful monitoring for possible complications is a vital part of myeloma treatment.
Bone Fractures
One of the earliest symptoms of multiple myeloma is pain in the lower back and ribs. This pain results from tiny... Read more >
The efficiency of multiple myeloma treatment depends on how advanced the cancer is at the time of diagnosis. Multiple myeloma stages are classified according to a number of criteria. Classification of cancer stages indicates which treatments are the most appropriate for the individual patient.
The Durie-Salmon Staging Classification System
Multiple myeloma is staged according to the Durie-Salmon classification... Read more >
Blood cancers are classified as "hematological malignancies," or cancers that affect the blood, bone marrow and lymph nodes. Because each of these bodily systems is closely connected through the immune system, cancer of one area often spreads to the other two. Blood cancer involves the uncontrolled growth of abnormal cells in the blood.
About Blood Cancer
In 2008, approximately 138,000 new cases of blood borne... Read more >
Primary bone cancer, which is diagnosed in fewer than 2,500 Americans annually, is more common in children than adults.
Primary bone cancer originates in the skeletal system. One of the least common forms of cancer, it occurs when a malignant tumor in the bone destroys normal bone tissue. Benign tumors in the bones also occur, and in fact are more common than malignant bone tumors, but they do not spread... Read more >